Actos (Pioglitazone)

What is Actos?

Actos or PioglitazoneActos (scientific name pioiglitazone) is a prescription drug that helps Type II diabetics control their blood sugar levels. In the United States, pioglitazone is also sold as Actoplus Met and Actoplus Met XR (in combination with metformin) and Duetact (in combination with glimepiride).

Actos belongs to a class of drugs called thiazolidinediones or glitazones. The class also includes the troubled medication Avandia (rosiglitazone), which may increase the risk of heart attack, and Rezulin (troglitazone), which was taken off the U.S. market in 2000 because of a risk of liver damage. As a result, Actos already carries a black box warning the FDA’s strongest about the risk of heart failure, as well as a warning about the potential for liver failure.

Is There A Link Between Actos and Bladder Cancer?

Recent research raises concerns about an association between long-term use of Actos and bladder cancer. Our attorneys represent clients across the nation who developed bladder cancer after taking Actos.

Bladder cancer is very aggressive, and can require chemotherapy, radiation and removal of part of the bladder, after which the patient may need an external bag for elimination.

Pharmaceutical companies, like all manufacturers, have a duty to warn patients about serious safety risks, and this obviously includes cancer. When they fail in that duty, you have the right to hold them legally and financially responsible for the results.

The FDA and Actos

The U.S. Food and Drug Administration announced in June 2011 an ongoing Actos study found the higher the dose and the longer patients took Actos, the more likely they were to develop bladder cancer. A French study published the same month also found an increased risk of bladder cancer, particularly for long-term patients and those taking higher doses. That study prompted the French drug regulator to suspend prescriptions of Actos entirely, and the German agency to stop prescriptions for new patients. In the United States, the FDA has not taken the drug off the market, but it did update the label to warn against using Actos in patients with active or past bladder cancer.

We Can Help

If you developed bladder cancer after taking Actos, do not hesitate to contact the St. Louis defective drug lawyers at E. Ryan Bradley. We represent patients who suffered serious injuries after taking a prescription drug, including developing a serious illness that the drug is now known to cause. Our Missouri Actos lawyers help clients prove a link between Actos and their cancer and collect compensation for their illness, lost quality of life, lost income and more.

E. Ryan Bradley offers free, confidential case evaluations, so you can talk to us about your case at no further risk or obligation. To set up a meeting, call us today at 314-400-0000.

Our Results

Our Personal Injury Attorneys have proudly collected TENS OF MILLIONS of dollars in compensation for clients. Below are some of our recent personal injury case results.

$30M Sexual Assault
$14.25M Motorcyle Crash
$10.5M Fatal Wreck
$4M Product Liability
$4M Wrongful Death
$2M 18-Wheeler Wreck
$2M Wrongful Death Trucking Crash
$2M Wrongful Death Tractor Trailer
$1.7M Van Crash
$1M Truck Crash
$1M 18-Wheeler Wreck
$321K Auto Crash
$300K Motorcycle Wreck
$300K SUV Wreck
$225K Truck Crash

View All Results →


What Our Clients Are Saying

"Overall, I had a great experience working with The Bradley Law Firm!! I would recommend Ryan and his team to anyone. Being involved in a car accident can be quite stressful and dealing with insurance companies can be even more stressful. Having Ryan in my corner lifted a huge burden off my shoulders and made this process much easier for me. They handled everything. Tina is great…she is awesome! She’s extremely patient and kept me informed throughout the entire process. The Bradley Law Firm team is very personable, easy to talk to, and a pleasure to work with."


St Louis Personal Injury Lawyer

Our Results

Our Personal Injury Attorneys have proudly collected TENS OF MILLIONS of dollars in compensation for clients.

St Louis Personal Injury Lawyer

Our Mission

It is our mission to ensure you receive a maximum recovery for all of your damages, to the fullest extent under the law.


We Maintain the Highest Possible Ratings from Professional Organizations


Our FirmPractice AreasContact UsSitemap

St. Louis Lawyer Disclaimer: The legal information offered herein, is not formal legal advice, nor is it the formation of an attorney client relationship. In order for our firm to be considered your attorney there must be a signed agreement between the client and the firm. Any results set forth herein are based solely upon the circumstances of that particular case and offer no promise or guarantee upon the outcome of any other case. Please contact a lawyer for a consultation. This site is not intended to solicit clients outside the State of Missouri or Illinois. The Bradley Law Firm may co-counsel or associate with other law firms around the country at its discretion from initial intake through litigation when it deems appropriate.

Follow Us on Social Media

Image Image Image
314-293-5753, 314-470-1786, 314-668-9253

© 2018, The Bradley Law Firm.

Bradley Law Firm Bradley Law Firm 1424 Washington Ave., #300 St. Louis, MO 63103 314-400-0000 Prices Vary St Louis Personal Injury Lawyer - 5 stars - based on 46 reviews